EMB – Embryology

Animal Caretaker-Facilities Support

Department: EMB – Embryology

Salary: Based on experience

Location: Baltimore, MD

Animal Caretaker-Facilities Support (Porter) – Full Time

Department: EMB – Embryology

Location: Baltimore, MD

Job Summary:

The Carnegie Institution for Science Department of Embryology seeks a hardworking, responsible and reliable person to join the department as an Animal Caretaker and Facilities support person (Evening Porter). This individual will perform daily maintenance and care for laboratory animals, as well as Facilities support tasks for the building.

Principle Responsibilities include:

Change dirty cages and provide food and water as required to maintain a clean and healthy environment for the animals

Observe animals daily and prepare routing reports on dead and sick animals

Observe and report problems involving animal care equipment and environmental support systems

Receive, identify and house selected animal species

Assist in specialized monitoring and surveillance programs

Prepare special diets in accordance with the principal investigator’s protocols, and ensure that the special diets are provided to the correct animals

Assist in the operation of standardizing, conditioning, and breeding programs

Administer commonly used and easily administered treatments or medication as directed by the Facility Manager

Perform basic manipulations such as restraining animals, tagging and tailing, etc.

Perform duties of other Animal Facility team members and other duties as assigned

Awareness of the critical aspects of laboratory safety

Assist in the training and supervision of new team members if requested by the Manager

Receiving packages on a daily basis and delivering them to the individual laboratories

Sanitizing and cleaning numerous surfaces as directed by the Facilities Manager

Collecting and disposing of trash on a daily basis

Washing floors throughout the building

Performing Facilities tasks as assigned by the Facilities Manager

Other Duties as assigned

Interactions with Others:

Work is performed under the immediate supervision of the Rodent Facility Manager with

Work methods are stated explicitly and neither require nor permit deviation.

Qualifications:

High School degree, equivalent or certification as animal technician

Previous animal care experience is a plus

Detail oriented

Reliable

Hardworking

Able to learn tasks with general instruction

Able to understand and follow work and safety protocols

Basic computer skills required

Physical Requirements:

Routinely stoops and bends

Routinely reaches and grasps with arms and hands above head

Routinely stands for long periods

Occasionally lifts, pushes and/or carries objects weighing up to 60 pounds

May be exposed to some unpleasant conditions associated with handling animals and disagreeable animal odors

To apply:

A brief cover letter and resumé/CV listing two professional references are required to apply. Apply online at:

https://jobs.carnegiescience.edu/jobs/emb/

Additional information:

The Department of Embryology is one of six departments comprising the Carnegie Institution for Science. The department functions as a private, non-profit research institute affiliated with the Johns Hopkins University and is located adjacent to the JHU Homewood campus in Baltimore, MD.

Carnegie is an equal opportunity employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of gender, race/ethnicity, protected veteran status, disability, or other protected group status.

 

Laboratory Technician – Cleves Lab

Department: EMB – Embryology

Salary: Based on experience

Location: Baltimore, MD

Laboratory Technician

Department: EMB – Embryology

Salary: TBD

Location: Baltimore, MD

Position Overview:

The Cleves lab is a newly established research group at the Carnegie Institution’s Embryology Department (https://emb.carnegiescience.edu/), located on the Johns Hopkins University Homewood campus in Baltimore, MD. We seek an enthusiastic and organized research technician for our laboratory.

Our new lab uses genetic, biochemical, and cell biology methods to understand the molecular and cellular bases of coral-algal symbiosis and its breakdown due to stress. We study corals in the field and utilize several tractable model organisms in the lab (e.g., the small anemone, Aiptasia). Our research is motivated both by the fascinating and poorly understood biology of corals and by the desire to help protect the world’s endangered coral reefs. This position provides an opportunity for a motivated, reliable, organized, and disciplined person to support and participate in this multidisciplinary research that has significant implications for both medicine and conservation biology.

This is a full-time position with competitive salary and benefits, with an anticipated start date in the fall of 2020 or early 2021.

Essential Job Duties:

  • Assisting with the husbandry and spawning of the lab’s sea anemone and algal cultures (e.g., feeding animals, cleaning and disinfecting aquarium tanks, breaking down aquarium tanks requiring the ability lift up to 40 pounds).
  • assays (e.g., microscopy, genotyping, and quantification of symbiont density)
  • Applying standard molecular biology methods (g., PCR, Gibson and other cloning methods, gel electrophoresis)
  • Meeting routinely with Dr. Cleves to discuss research progress, priorities, and strategies
  • Attending weekly laboratory meetings and preparing regular oral presentations
  • Maintaining precise records of work, in both hand-written and electronic formats
  • Maintaining the cleanliness of shared lab spaces
  • Assisting with support duties relating to general lab management and organization
  • Maintaining professional conduct that supports a collaborative, collegial, and inclusive research environment
  • Helping orient and train new staff and students

Desired Qualifications:

  • Familiarity with marine organisms and/or with aquarium maintenance
  • Familiarity with fieldwork on marine organisms
  • Experience in molecular and cell biology

While these qualifications are desired, curious candidates from any area of life sciences who are enthusiastic about learning are encouraged to apply.

Required Education & Skills:

  • Applicants must have a Bachelor’s or Master’s degree in life sciences or related disciplines with at least one year of experience working in a research laboratory
  • General understanding of scientific principles
  • General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications
  • Ability to work under deadlines with general guidance
  • Excellent organizational skills and demonstrated ability to accurately complete detailed work

To be considered for this position, please send the following materials by e-mail to Dr. Cleves (cleves@carnegiescience.edu) as a single PDF:

  • Brief cover letter including long-term career goals
  • CV emphasizing prior research experience
  • Contact information for three references
  • Undergraduate and/or graduate transcripts (unofficial copies are fine)

Priority will be given to candidates who apply by September 1, 2020. Applications will continue to be accepted until the position is filled.

Additional information:

The Department of Embryology is one of six departments comprising the Carnegie Institution for Science. The department functions as a private, non-profit research institute affiliated with the Johns Hopkins University and is located adjacent to the JHU Homewood campus in Baltimore, MD. The department consists of 10 laboratories studying a variety of questions in cell and developmental biology. For more information about the Department, visit https://emb.carnegiescience.edu/. Carnegie is an equal opportunity employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of gender, race/ethnicity, protected veteran status, disability, or other protected group status. 

Laboratory Technician

Department: EMB – Embryology

Salary: Based on experience

Location: Baltimore, MD

Position Overview:

The Belin lab (http://www.belinlab.org) is a newly established research group at the Carnegie Institution’s Embryology Department (https://emb.carnegiescience.edu/), located on the Johns Hopkins University Homewood campus in Baltimore, MD. We seek an enthusiastic and motivated technician to assist in our research on the cell biology of nitrogen-fixing soil bacteria and their symbioses with plant hosts. This is a full-time position with competitive salary and benefits, with an anticipated start date during the fall of 2020.

Specific research responsibilities will depend on the candidate’s scientific interests and background, but will generally include:

  • Preparing media and maintaining bacterial cultures and stocks using sterile technique
  • Applying standard molecular biology methods (g. PCR, Gibson and other cloning methods, gel electrophoresis) to generate transgenic bacterial strains
  • Cultivating soybeans and other legumes in plant growth chambers, including assisting other lab members in maintaining their plants as needed
  • Meeting routinely with Dr. Belin to discuss research progress, priorities and strategies
  • Attending weekly laboratory meetings and preparing regular oral presentations
  • Maintaining precise records of work, in both hand-written and electronic formats
  • Maintaining the cleanliness of shared lab spaces
  • Assisting with support duties relating to general lab management and organization
  • Maintaining professional conduct that supports a cooperative, collegial and inclusive research environment

Applicants must hold a Bachelor’s or Master’s degree in life sciences or related discipline, with at least one year of experience working in a life sciences research laboratory. While plant or microbial biology expertise is desirable, highly curious candidates from any area of life sciences who are enthusiastic about learning new skills and expertise are encouraged to apply.

To be considered for this position, please send the following materials by e-mail to Dr. Belin (belin@carnegiescience.edu) as a single PDF:

  • Brief cover letter including long-term career goals
  • Résumé emphasizing prior research experience
  • Contact information for three references
  • Undergraduate and/or graduate transcripts (unofficial copies are fine)
  • Publications (if available)

Priority will be given to candidates who apply by August 1, 2020. Applications will continue to be accepted until the position is filled.

Additional information:

The Department of Embryology is one of six departments comprising the Carnegie Institution for Science. The department functions as a private, non-profit research institute affiliated with the Johns Hopkins University and is located adjacent to the JHU Homewood campus in Baltimore, MD. The department consists of 10 laboratories studying a variety of questions in cell and developmental biology. For more information about the Department, visit https://emb.carnegiescience.edu/

Carnegie is an equal opportunity employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of gender, race/ethnicity, protected veteran status, disability, or other protected group status. 

Postdoctoral Fellow

Department: EMB – Embryology

Salary: TBD

Location: Baltimore, MD

Overview:

The Zheng Lab at the Carnegie Institution’s Department of Embryology seeks ambitious postdoctoral fellows interested in understanding the role of lamins in mouse development. The Zheng lab has developed mouse models that allow the study of individual and different combinations of the three lamin genes using germline or conditional lamin knockout. The lab also developed mouse embryonic stem cells lacking all or different combinations of lamins. By employing a wide range of genomic tools and cell biological approaches, the lab has observed a number of interesting phenotypes in different lamin knockout combinations. We seek a postdoctoral fellow with skills in analyzing mouse early embryos, ES cell derivation, and the use of ES cells to study differentiation.

Selected publications:

  1. Kim Y…Zheng Y (2011). Mouse ES cells do not need any lamins but proper organogenesis requires lamin-Bs. Science 334:1706-1710.
  1. Jia J…Zheng Y (2012). Regulation of pluripotency and self-renewal of ES cells through epigenetic threshold modulation and mRNA pruning. Cell 151:576–589.
  1. Chen H, Chen X, and Zheng Y (2013). The nuclear lamina regulates germline stem cell niche organization via modulation of EGFR signaling. Cell Stem Cell 13:73-86.
  2. Chen H, Zheng X, and Zheng Y (2014). Age-associated loss of lamin-B leads to systemic inflammation and gut hyperplasia. Cell 159:829-843. Zheng X…Zheng Y (2018). Lamins organize the global three-dimensional genome from the nuclear periphery. Molecular Cell DOI: https://doi.org/10.1016/j.molcel.2018.05.017 .
Additional Information:

The Department of Embryology is one of six departments comprising the Carnegie Institution for Science. The department functions as a private, non-profit research institute affiliated with the Johns Hopkins University and is located adjacent to the JHU Homewood campus in Baltimore, MD. The department consists of 10 laboratories studying a variety of questions in cell and developmental biology. For more information about the Department, visit https://emb.carnegiescience.edu/

Carnegie is an equal opportunity employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of gender, race/ethnicity, protected veteran status, disability, or other protected group status.

Please submit a copy of your resume or CV with the application.  If you have further questions please reach out to Dr. Yixian Zheng, Principal Investigator.

 

 

Postdoctoral Fellow-Kostova Lab

Department: EMB – Embryology

Salary: TBD

Location: Baltimore, MD

Overview: A postdoctoral position is available in the laboratory of Dr. Kamena Kostova (https://kostovalab.org/) at the Carnegie Institution for Science, Department of Embryology in Baltimore, MD. We are investigating the fundamental question of how cells respond when their ribosomes break down. The ribosome is one the most complex and long-lived molecular machines in the cell and the presence of functional ribosomes is essential to live. Ribosome damage has been recently linked to complex human diseases, such as cancer and neurodegeneration. We use cutting-edge technology, such as CRISPR-Cas9-mediated genome editing and genome scale screens, to model and map the molecular pathways that ensure ribosome integrity in mammalian cell lines and zebrafish.

Qualifications: An ideal candidate will be creative, industrious, have excellent communication skills, and enjoy working independently as well as collaboratively. A Ph.D. in a related field and fluency in spoken and written English is required for the position.

To apply: Please send a curriculum vitae, statement of research interest, and contact information for three references to kostova@carnegiescience.edu.

Additional Information:

The Department of Embryology is one of six departments comprising the Carnegie Institution for Science. The department functions as a private, non-profit research institute affiliated with the Johns Hopkins University and is located adjacent to the JHU Homewood campus in Baltimore, MD. The department consists of 10 laboratories studying a variety of questions in cell and developmental biology. For more information about the Department, visit http://emb.carnegiescience.edu/

Carnegie is an equal opportunity employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of gender, race/ethnicity, protected veteran status, disability.